Cell Manufacturing Technician

Ncardia is an established, globally operating, stem cell-based drug discovery & cell therapy company. At Ncardia, we believe that stem technology will help get better therapies to patients faster. The goal of the company is to be the supportive and trusted partner for scientists operating within the human induced pluripotent stem cell (hiPSC) drug discovery and cell therapy fields, and in particular, in the cardiovascular and neurology space.

Ncardia develops, produces, and commercializes highly predictive human cardiovascular and neurological cellular assay systems. In addition, Ncardia develops and provides its customers with a broad portfolio of services from cardiovascular and neuronal disease modeling to target discovery and validation, primary or secondary drug screening, hit to lead and lead optimization, safety assessment, and pre-clinical patient stratification.

We are an enthusiastic, skilled, and committed international team in which everyone has the opportunity to make a decisive contribution. Within our Drug Discovery team in Leiden (The Netherlands) there is a position immediately available for a Technician Cell Manufacturing.

Job Description

The Cell Manufacturing Technician is a laboratory-based role which will involve all aspects of client projects for process development, custom manufacturing and characterization of iPSC-derived cells under supervision of subject matter experts. Activities include advanced stem cell culture, state of the art stem cell differentiation processes, down-stream processing and being co-responsible for laboratory activities during week-ends and public holidays. 

Responsibilities

• Perform state of the art cell culture techniques in the field of human stem cell maintenance

• Perform custom production (adherent culture or bioreactor-based) and cryopreservation of functional iPSC-derived cell types

• Execute studies for the development of novel iPSC-derived cell types

• Perform in process analyses during cell production

• Perform cell-based assays for functional characterization of differentiated cells

• Support routine lab activities such as solution stock keeping and equipment maintenance

• Perform week-end work incidentally if needed

• Collect and record data accurately following standard operation procedures

• Propose solutions and participate in investigations whenever needed 

Required experience

• Vocational Education and Training (MBO) or bachelor degree in (applied) biological science or related domains

• Demonstrated practical experience in cell culture techniques is a requirement (such as, maintenance of cell lines, cryopreservation, cell counting, media preparation, aseptic techniques)

• Experience with stem cells is a plus

• Experience with flow cytometry/immunofluorescence/cell-based assays is a plus

• Experience with stirred-tank bioreactors is a plus

Required skills

• Pro-active mindset, well-organized, accurate and reliable

• Highly motivated and dedicated team worker

• Good communication skills and team-player

• Understanding of good documentation practice

• Excellent knowledge of English both written and verbal

We offer a challenging position in a dynamic biotech company with room for personal growth and development. Depending on your education and experience, we provide an appropriate salary.

Position Type

Full-Time

Start Date

Immediately

Interested?

Send your motivation letter with curriculum vitae to: careers@ncardia.com