This poster presents Ncardia’s bioreactor-produced human iPSC-derived ventricular cardiomyocytes integrated into engineered heart tissues (EHTs), combining scalable cell manufacturing with physiologically relevant contractility testing for translational cardiac safety assessment.
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How Ncyte® vCardiomyocytes are manufactured at scale in controlled stirred-tank bioreactors and incorporated into 3D engineered heart tissues
How the MyoPod® and MyoLab® platforms enable real-time assessment of contractile force, tissue dynamics and pharmacological responses
Functional data showing a robust β-adrenergic response to isoproterenol, including increased peak force and accelerated contraction and relaxation kinetics
How the engineered tissues demonstrate positive force-frequency behaviour and physiological length-dependent activation
How scalable hiPSC-vCM manufacturing and 3D contractility testing can be combined to support translational cardiac safety pharmacology workflows