---
title: Human iPSC Tri-Culture for Alzheimer’s Disease Poster
description: See how Ncardia’s iPSC-derived tri-culture model advances Alzheimer’s disease drug discovery.
---

[Resources ](https://www.ncardia.com/insights/resources)

# [Human iPSC Tri-Culture for Alzheimer’s Disease Poster](https://www.ncardia.com/insights/resources/human-ipsc-tri-culture-for-alzheimers-disease-poster)

 Written by [Ncardia Stem Cell Experts](https://www.ncardia.com/insights/resources/author/ncardia) | November 3, 2025

This poster highlights the development and validation of Ncardia’s human [iPSC-derived](https://www.ncardia.com/our-approach/ipsc-technology) tri-culture model for Alzheimer’s disease (AD), offering a physiologically relevant system to study neuroinflammation, tau pathology and neuronal degeneration in vitro.

Download it now for a closer look at:

- How Ncardia’s tri-culture of [neurons](https://www.ncardia.com/cell-supply/ncyte-astrocytes), [astrocytes](https://www.ncardia.com/cell-supply/ncyte-astrocytes) and [microglia](https://www.ncardia.com/cell-supply/ncyte-microglia) mimics key aspects of human brain physiology and AD pathology 
- Quantitative data demonstrating microglia activation via cytokine secretion, protein aggregation, and neuronal changes reflective of AD progression
- Why co-culturing all three CNS cell types enhances physiological relevance 
- Insights into therapeutic screening applications for mitigating neuroinflammation and protein aggregation

[ Download the Poster ](https://www.ncardia.com/insights/resources/human-ipsc-tri-culture-for-alzheimers-disease-poster?hs_amp=true#download-resource)

[View full post](https://www.ncardia.com/insights/resources/human-ipsc-tri-culture-for-alzheimers-disease-poster)

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