This poster highlights the development and validation of Ncardia’s human iPSC-derived tri-culture model for Alzheimer’s disease (AD), offering a physiologically relevant system to study neuroinflammation, tau pathology and neuronal degeneration in vitro.
Download it now for a closer look at:
- How Ncardia’s tri-culture of neurons, astrocytes and microglia mimics key aspects of human brain physiology and AD pathology
- Quantitative data demonstrating microglia activation via cytokine secretion, protein aggregation, and neuronal changes reflective of AD progression
- Why co-culturing all three CNS cell types enhances physiological relevance
- Insights into therapeutic screening applications for mitigating neuroinflammation and protein aggregation
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