---
title: iPSC-Based Parkinson’s Disease Model Poster
description: Get an exclusive look at how Ncardia’s iPSC-derived dopaminergic neuron model advances Parkinson’s disease research.
---

[Resources ](https://www.ncardia.com/insights/resources)

# [iPSC-Based Parkinson’s Disease Model Poster](https://www.ncardia.com/insights/resources/ipsc-based-parkinsons-disease-model-poster)

 Written by [Ncardia Stem Cell Experts](https://www.ncardia.com/insights/resources/author/ncardia) | November 3, 2025

Ncardia developed a human iPSC-derived dopaminergic neuron model to capture the key pathological hallmarks of [Parkinson’s disease (PD)](https://www.ncardia.com/insights/resources/drug-discovery-parkinsons-disease), providing a robust platform for screening potential therapeutics and studying disease mechanisms in vitro. 

This poster offers an inside look, detailing:

- How Ncardia’s iPSC-derived dopaminergic neurons replicate α-synuclein (SNCA) pathology and enable assessment of neurodegenerative phenotypes 
- High-content imaging and electrophysiology data revealing mitochondrial dysfunction, disrupted proteasomal activity and neuronal network changes 
- Insights into how PD-relevant phenotypes can be rescued with pharmacological intervention (e.g., rapamycin) 
- [Quantitative assays](https://www.ncardia.com/discovery-services/ready-to-use-assays) assessing cellular and functional readouts

[ Download the Poster ](https://www.ncardia.com/insights/resources/ipsc-based-parkinsons-disease-model-poster?hs_amp=true#download-resource)

[View full post](https://www.ncardia.com/insights/resources/ipsc-based-parkinsons-disease-model-poster)

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