---
title: iPSC Platforms for RNA Therapeutics Efficacy & In Vivo Toxicity Poster
description: Explore Ncardia’s iPSC-derived platform and hot it enables early efficacy and neurotoxicity screening for RNA therapeutics.
---

[Resources ](https://www.ncardia.com/insights/resources)

# [iPSC Platforms for RNA Therapeutics Efficacy & In Vivo Toxicity Poster](https://www.ncardia.com/insights/resources/ipsc-platforms-for-rna-therapeutics-efficacy-in-vivo-toxicity-poster)

 Written by [Ncardia Stem Cell Experts](https://www.ncardia.com/insights/resources/author/ncardia) | November 3, 2025

By combining automated workflows with physiologically relevant human models, Ncardia’s innovative iPSC-based platforms offer a more predictive, scalable and efficient approach to [RNA therapeutic development](https://www.ncardia.com/discovery-services/modalities/ipsc-platform-rna-therapeutics).

Download it now for a closer look at:

- How Ncardia’s automated RT-qPCR assay achieves high reproducibility in [antisense oligonucleotide (ASO) screening](https://www.ncardia.com/insights/resources/how-to-design-relevant-aso-invitro-screening) across multiple iPSC-derived cell types 
- Use of hiPSC-derived cortical neurons and CNS cultures to assess both target knockdown and dose-dependent neurotoxicity 
- Functional insights from calcium transient and MEA assays identifying neuronal excitability and network disruptions 
- How these assays enable early, human-relevant predictions of *in vivo* toxicity, reducing animal use and improving translational confidence 

[ Download the Poster ](https://www.ncardia.com/insights/resources/ipsc-platforms-for-rna-therapeutics-efficacy-in-vivo-toxicity-poster?hs_amp=true#download-resource)

[View full post](https://www.ncardia.com/insights/resources/ipsc-platforms-for-rna-therapeutics-efficacy-in-vivo-toxicity-poster)

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