---
title: "Scientific poster: Evaluating compound binding and MoA with human iPSC-derived atrial cardiomyocytes"
description: This scientific poster describes how we supported target identification and confirmed mechanism of action with Ncardia's human iPSC-derived models and screening services
---

[Resources ](https://www.ncardia.com/insights/resources)

# [Scientific poster: Evaluating compound binding and MoA with human iPSC-derived atrial cardiomyocytes](https://www.ncardia.com/insights/resources/scientific-poster-acardiomyocytes-for-sar-moa-studies)

 Written by [Ncardia Stem Cell Experts](https://www.ncardia.com/insights/resources/author/ncardia) | July 25, 2024

In this study, we support the client on assessing cardiotoxicity and identifying the mechanism of action (MOA) through functional and gene expression means. Our hiPSC-derived atrial-like cardiomyocytes (aCMs) and control Ncyte®  vCardiomyocytes were manufactured and characterized according to this specific research project. Then, cells were seeded into multi-electrode array (MEA) plates and treated with a panel of control compounds with the aim to identify drug targets, support SAR and determine mechanisms of action.

The results demonstrate the potential of Ncardia's hiPSC-derived models and custom screening services, as a robust and physiologically relevant platform to accelerate and de-risk the development of new therapeutic strategies. 

 

[View full post](https://www.ncardia.com/insights/resources/scientific-poster-acardiomyocytes-for-sar-moa-studies)

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