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Ncyte CNS Neuron Kit II

The Ncyte CNS Neuron Kit II comprises of two key cell types of the human central nervous system: neurons and astrocytes. The cells are simultaneously generated from neural precursor cells and recapitulate the interplay between excitatory and inhibitory neurons. Their rapid formation of neuronal networks, prolonged viability in culture, and availability in unlimited volumes, make the Ncyte CNS Neuron Kit advantageous for neuroscience applications, compared to primary cells and animal models.

The Ncyte CNS Neuron Kit is ideal for early and late drug discovery for neurodegenerative disease and epilepsy, in vitro neurotoxicity assays, and disease modeling, through electrophysiological, metabolic and imaging-based assays. This 2nd generation of the Ncyte CNS Neuron Kit is created to increase the neuronal network’s performance: neuronal firing can be detected earlier, in more complex and structured patterns, for a longer period of time.

Product description

The Ncyte CNS Neuron Kit II is a tool for drug discovery in neurodegenerative disease and epilepsy, neurotoxicity assays, and disease modeling, through its application in electrophysiological, metabolic and imaging assays. The Ncyte CNS Neuron Kit II contains cryopreserved, human iPSC-derived neurons and astrocytes, medium and supplement.

We use our Ncyte CNS Neuron Kit II in drug discovery research for neurodegenerative diseases. Learn how you can leverage our experience for your project: https://www.ncardia.com/neurodegenerative-diseases/

Product specifications

Catalog number

Nc-K-CNS-2

Kit contents

2M vial viable Ncyte CNS Neuron cells per vial

250 mL Ncyte Neuronal Basal Medium (Cat. #: Nc-M-NBM)

2 vials of 1.25 mL Ncyte Neuronal Supplement (Cat. #: Nc-MS-NNS)

Key biomarkers

ßIII tubulin, GABA, vGLUT1, MAP2, GFAP, TH

Assay window

Neuronal spike activity (MEA) starting at day 4, progressive maturation of electrical network, synchronized bursting within two weeks

Storage recommendations

Ncyte CNS Neuron cells: liquid nitrogen

Ncyte Neuronal Basal Medium: 2-8°C

Ncyte Neuronal Supplement: -80°C

Selected data

Documentation