Ncardia Stem Cell Experts

Unlocking the secrets of muscular disease using iPSC models

December 15, 2022 at 9:00 ET / 15:00 CET

Nov 22_ Webinar Mariana (1)

Human induced pluripotent stem cell (iPSC)-based disease models provide an advantageous platform for drug discovery. Several available models have contributed to advances in cardiac and neurological research. With the advance of iPSC differentiation techniques, more cell-relevant disease models are available to explore, including those for muscle diseases such as Duchenne’s Muscular Dystrophy.

Nevertheless, implementation of iPSC-derived models in drug discovery projects involves several critical considerations. For instance, lineage specification of iPSCs to cell types that closely recapitulate key disease features and cell manufacturing at a commercial scale. Another critical step is reproducibility and development of high-throughput assays that measure the disease biology.

During this webinar we will discuss the advantages, challenges, and solutions of implementing iPSC-technology into drug discovery and development for muscle disease modeling.

Complete the form below to join this webinar and learn more about:

  • The advantages of iPSC-derived disease models
  • The critical considerations when implementing iPSC-based models
  • The iPSC-based model of Duchenne's Muscular Dystrophy and its advantages and challenges.