Gain the advantage with high-throughput screening of iPSC-derived models
Pair Ncardia’s iPSC-derived disease models and high-throughput screenings to get clinically relevant readouts earlier in drug discovery
Reliable high-throughput screening
for a clearer perspective
At Ncardia, our assays are developed by an expert team who ensures an efficient development process and delivery of robust and reproducible outcomes that help advance your project. Our customized high-throughput phenotypic screenings are based on physiologically relevant iPSC models and focus on the modulation of disease-linked phenotypes. This strategy enables both testing compounds’ efficacy and safety in human biology earlier and screening with readouts similar to the ones used in clinical trials, which helps you narrow in on your compounds that have a higher probability of success.
Benefits of Ncardia Screening
Evaluate disease-specific phenotypes with the most relevant readouts
Increased chance of success
Consistent and clinically relevant outcomes
Select compounds with high
probability of clinical success
Efficacy and safety screening with
iPSC-based in vitro models
At every stage of your drug discovery project – whether it’s target identification, lead finding or safety assessment – a reliable assay is the key to success. Our phenotypic screening of iPSC-based disease models makes it easier to extrapolate to the clinical situation.
We work together with you to accelerate your research and successfully bring your project to the next stage - by meeting your milestones and ensuring compliant, on-time assay results through several stages of your drug discovery process.
Study compound-induced effects on blood vessel formationAssay Biomarker detection
Evaluate and quantify the levels of clinically relevant biomarkersAssay Calcium transients
Obtain real-time recordings of intracellular calcium fluctuationsAssay Contractility
Study drug-induced effects on contractility of cardiac or skeletal muscle cellsAssay Electrophysiology
Determine the electrophysiological effects of your therapeutic candidatesAssay Endothelial barrier function
Evaluate endothelial permeability in short and long termAssay High content imaging
Study drug-induced phenotypic changes in the cell model of your interestAssay Metabolism
Obtain precise information on compounds' impact on metabolic processes
Screening that passes
the toughest tests
As more and more drug discovery innovators look to capitalize on the unique value only iPSCs can deliver, they look to Ncardia as the uniquely qualified collaborator to join them on their all-important journeys. We’re ready to help make your next step the very best it can be. So let’s start with a conversation – about your vision, goals and expectations for your drug discovery projects.