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NHP iPSC-Derived Cardiomyocytes for Translational Cardiac Profiling

A Translational in-vitro platform of Non-Human Primate iPSC-derived ventricular cardiomyocytes for functional profiling
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This poster presents Ncardia’s non-human primate (NHP) iPSC-derived ventricular cardiomyocyte platform, designed to bridge the gap between in vitro and in vivo studies for gene and cell therapy development. 

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  • How NHP iPSC-derived cardiomyocytes can be produced at scale with high purity and stable functional properties, supporting consistent experimental outcomes 
  • Comparative data highlighting key electrophysiological and contractile differences between human and NHP cardiomyocytes under baseline and drug-treated conditions 
  • Insights into species-specific responses to pharmacological compounds, supporting better interpretation of translational safety data
  • How this platform enables repeated, long-term functional assessment in a controlled in vitro environment, complementing in vivo NHP studies
  • How integrated MEA and impedance assays enable detailed functional profiling, including beat rate, arrhythmia, and contractility responses over time 

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Whether you are developing gene or cell therapies, this platform provides a scalable, translationally relevant system to evaluate functional outcomes and bridge preclinical findings across species with greater confidence.

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