Human iPSC-Derived Tri-Culture Model for Neuroinflammation and Neurodegeneration

This poster highlights the development and validation of Ncardia’s human iPSC-derived tri-culture model, providing a physiologically relevant in vitro platform to study neuroinflammation, tau pathology, and neuronal dysfunction in neurodegenerative disease research.

Download it now for a closer look at:

• How Ncardia’s tri-culture system combines neurons, astrocytes, and microglia to recreate key cellular interactions involved in neurodegeneration and inflammatory signaling
  
• Quantitative data demonstrating microglial activation through cytokine release, phagocytic activity, and Tau-related pathological changes
• Why integrating all three CNS cell types improves physiological relevance compared to conventional monoculture systems
• How the platform enables miniaturized tauopathy assays using Tau pre-formed fibrils to model disease-relevant neurodegenerative processes

• Insights into therapeutic screening applications targeting neuroinflammation, Tau aggregation, and neuronal dysfunction