Human iPSC-Derived 3D Cardiac and Brain Microtissues for Drug Discovery

This poster presents Ncardia’s scalable human iPSC-derived 3D cardiac and brain microtissue platforms, developed to improve disease modelling, drug discovery, and toxicology assessment through more physiologically relevant in vitro systems.

Download it now for a closer look at:

• How 3D cardiac and brain microtissues recreate multicellular interactions and functional complexity beyond traditional 2D models
  
• Functional validation data showing physiologically relevant responses in cardiac microtissues, including chronotropic and inotropic effects following compound treatment
• How Heart in Box™ microtissues support disease modelling and high-throughput screening, including a ~2,000 compound CPVT1 screening campaign completed in just two days
• Characterization of brain microtissues containing neurons, astrocytes, and microglia, with evidence of synaptic maturation and network formation over time

• How the platform can be adapted to model neurodegenerative disease mechanisms, including Tau aggregation relevant to Alzheimer’s disease