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Large-Scale Manufacturing for Reproducible iPSC-Based Drug Screening

Building manufacturing processes for reproducible, multi-year iPSC-based drug screening
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This poster presents Ncardia’s large-scale manufacturing platform for producing reproducible, high-quality iPSC-derived cellular models designed to support multi-year drug screening programs with consistent assay performance and scalable supply.

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  • How fully controlled stirred-tank bioreactor manufacturing enables reliable large-batch production of iPSC-derived cell models at industrial scale 
  • How data-driven monitoring of critical process and quality attributes supports reproducibility, consistency, and long-term assay stability
  • Characterization data across multiple iPSC-derived models, including ventricular and atrial cardiomyocytes, NHP cardiomyocytes, microglia, and 3D cardiac microtissues
  • Functional assay data demonstrating physiologically relevant responses to pharmacological compounds across electrophysiology, contractility, calcium handling, and inflammatory readouts
  • How standardized yet flexible manufacturing workflows support tailored differentiation strategies while maintaining robust batch-to-batch consistency

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Whether you are running high-throughput screening programs or developing advanced human-relevant assays, this platform provides scalable, reproducible iPSC-derived models designed to support long-term drug discovery and translational research.

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