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Advancing cardiovascular drug discovery with iPSC-Derived 3D cardiac microtissues in HTS

Scalable iPSC-derived 3D cardiac microtissues for automated high-throughput cardiovascular screening
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This poster presents Ncardia’s iPSC-derived 3D cardiac microtissue platform, designed for scalable and automated high-throughput screening while maintaining physiological relevance and functional robustness over time.

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  • How fully automated workflows enable the formation, maintenance, and functional analysis of 3D cardiac microtissues at screening scale

  • Functional validation data showing reproducible pharmacological responses, including chronotropic and inotropic effects, across large compound screens

  • Application of the Heart in a Box platform in ischemia–reperfusion and inherited arrhythmia disease models, supporting both safety and discovery use cases

  • Why integrating 3D cardiac microtissues into HTS pipelines improves translational relevance without compromising throughput or operational efficiency


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Whether enabling large-scale compound screening or supporting disease-specific cardiac models, Ncardia’s Heart in a Box platform provides a reproducible, automated foundation for human-relevant cardiovascular screening at scale. 

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